[Disorders of blood rheology in Walker's carcinosarcoma-256 and in cyclophosphamide treatment of rats]
- PMID: 11544834
[Disorders of blood rheology in Walker's carcinosarcoma-256 and in cyclophosphamide treatment of rats]
Abstract
Tumor process development in rats inoculated with cellular suspension of transplantable Walker's carcinosarcoma-256 involved enhanced thickening of blood on day 7. Treatment with 20 mg/kg cyclophosphamide, thrice a day, every other day, retarded tumor process and brought hemorheologic indices further down, at the same time. Similar treatment of intact rats with cyclophosphamide caused hemorheologic disorders too.