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. 2001 Sep;57(3):972-4.
doi: 10.1111/j.0006-341x.2001.00972.x.

A simple algorithm for designing group sequential clinical trials

D A Schoenfeld  1
Affiliations

A simple algorithm for designing group sequential clinical trials

D A Schoenfeld. Biometrics. 2001 Sep.

Abstract

This article describes a simple algorithm for calculating probabilities associated with group sequential trials. This allows the choice of boundaries that may not be among those implemented in available software.

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