Recurrent networks in human visual cortex: psychophysical evidence

Abstract

To study the neuronal circuitry underlying visual spatial-integration processes, we measured the effect of short and long chains of proximal Gabor-signal (GS) flankers (sigma = lambda = 0.15 degrees) on the contrast-discrimination function of a foveal GS target. We found that the same pattern of lateral masks enhanced target detection with low-contrast pedestals and strongly suppressed the discrimination of a range of intermediate pedestal contrasts (pedestal contrast <30%). Increasing the number of the flankers reversed the suppressive effect. The data suggest that the main influence of the proximal flankers is maintained by activity-dependent interactions and not by linear spatial summation. With an increased number of flankers, we found a nonmonotonic relationship between the discrimination thresholds and the number of flankers, supporting the notion that the discrimination thresholds are mediated by excitatory-inhibitory recurrent networks that manifest the dynamics of large neuronal populations in the neocortex [Proc. Natl. Acad. Sci. USA 94, 10426 (1997)].