Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2001 Sep 20;3(19):3009-12.
doi: 10.1021/ol016420q.

Synthesis of (-)-epibatidine

D A Evans  1 , K A Scheidt, C W Downey
Affiliations

Synthesis of (-)-epibatidine

D A Evans et al. Org Lett. .

Abstract

The synthesis of (-)-epibatidine has been accomplished utilizing a highly exo-selective asymmetric hetero Diels-Alder reaction. The key steps employed to transform the resulting bicycle into the natural product include a fluoride-promoted fragmentation and a Hofmann rearrangement. Reaction: see text.

PubMed Disclaimer

Publication types

MeSH terms

LinkOut - more resources