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Comparative Study
. 2001 Oct;9(10):2693-708.
doi: 10.1016/s0968-0896(01)00204-8.

Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues

A LeTiran  1 , J P Stables, H Kohn
Affiliations
Comparative Study

Functionalized amino acid anticonvulsants: synthesis and pharmacological evaluation of conformationally restricted analogues

A LeTiran et al. Bioorg Med Chem. 2001 Oct.

Abstract

Proven conformationally restricted analogues of anticonvulsant functionalized amino acids (FAAs) were prepared using short-range cyclizations and evaluated in pharmacological assays providing new information concerning the structural requirements for FAA function.

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