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Comment
. 2001 Sep;39(9):3423-4.
doi: 10.1128/JCM.39.9.3423-3424.2001.

IS6110 insertions in Mycobacterium tuberculosis: predominantly into coding regions

Comment

IS6110 insertions in Mycobacterium tuberculosis: predominantly into coding regions

S Sampson et al. J Clin Microbiol. 2001 Sep.
No abstract available

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Figures

FIG. 1
FIG. 1
Distribution of IS6110 insertion loci relative to open reading frames (ORFs) of the Mycobacterium tuberculosis H37Rv genome. The ORF numbers of the disrupted genes are indicated in bold, while the intergenic insertions are represented by two ORF numbers separated by a colon. The M. tuberculosis H37Rv insertion sites are underlined. Multiple integration sites within a single gene or intergenic region are denoted by multiple entries with the same name. The relative positions of the DR region and the ipl locus are shown, and the positions of regions deleted from M. tuberculosis H37Rv relative to M. bovis are indicated by their RvD numbers.

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References

    1. Beggs M L, Eisenach K D, Cave M D. Mapping of IS6110 insertion sites in two epidemic strains of Mycobacterium tuberculosis. J Clin Microbiol. 2000;38:2923–2928. - PMC - PubMed
    1. Benjamin W H, Jr, Lok K H, Harris R, Brook N, Bond L, Mulcahy D, Robinson N, Pruitt V, Kirkpatrick D P, Kimerling M E, Dunlap N E. Identification of a contaminating Mycobacterium tuberculosis strain with a transposition of an IS6110 insertion element resulting in an altered spoligotype. J Clin Microbiol. 2001;39:1092–1096. - PMC - PubMed
    1. Fang Z, Forbes K J. A Mycobacterium tuberculosis IS6110 preferential locus (ipl) for insertion into the genome. J Clin Microbiol. 1997;35:479–481. - PMC - PubMed
    1. Philipp W J, Poulet S, Eiglmeier K, Pascopella L, Balasubramanian V, Heym B, Bergh S, Bloom B, Jacobs W J, Cole S T. An integrated map of the genome of the tubercle bacillus Mycobacterium tuberculosis H37Rv, and comparison with Mycobacterium leprae. Proc Natl Acad Sci USA. 1996;93:3132–3137. - PMC - PubMed
    1. Sampson S L, Warren R M, Richardson M, van Der Spuy G D, van Helden P D. Disruption of coding regions by IS6110 insertion in Mycobacterium tuberculosis. Tuberc Lung Dis. 1999;79:349–359. - PubMed

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