doi: 10.1126/science.11560.
Presynaptic facilitation as a mechanism for behavioral sensitization in Aplysia
- PMID: 11560
- DOI: 10.1126/science.11560
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Presynaptic facilitation as a mechanism for behavioral sensitization in Aplysia
Science.
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Abstract
Sensitization is an elementary form of nonassociative learning, related to behavioral arousal, in which a strong stimulus facilitates a reflex response. Studies of the neural circuit of the gill-withdrawal reflex in the isolated abdominal ganglion on Aplysia indicate that short-term sensitization is due to presynaptic facilitation. The facilitation results in a sudden increase in the amount of neurotransmitter released by the sensory neurons at their synapses with motor neurons.
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