Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Oct;5(5):449-53.
doi: 10.1007/s11916-001-0056-4.

Estrogen and tension-type headache

Affiliations
Review

Estrogen and tension-type headache

D A Marcus. Curr Pain Headache Rep. 2001 Oct.

Abstract

The vast majority of people experience tension-type headache during their lifetimes. Boys experience tension-type headache slightly more than girls during preadolescent years. During adolescence and adult years, tension-type headache occurs more commonly in females. Tension-type headache changes in women occur in relation to gynecologic changes, including menses, pregnancy, and menopause. These changes are related to estrogen fluctuations. Estrogen fluctuations cause changes in neurochemicals important for pain signal transmission, including serotonin, gamma-aminobutyric acid, and enkephalins.

PubMed Disclaimer

Similar articles

Cited by

References

    1. Headache. 1996 May;36(5):285-90 - PubMed
    1. Headache. 1995 Jul-Aug;35(7):397-403 - PubMed
    1. Headache. 2000 Nov-Dec;40(10):783-91 - PubMed
    1. J Neurosci. 1994 Oct;14(10):6196-204 - PubMed
    1. Eur J Neurosci. 1996 Nov;8(11):2440-5 - PubMed