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Review
. 2001 Nov;7(17):1781-821.
doi: 10.2174/1381612013397140.

DNA-photocleavage agents

T Da Ros  1 , G Spalluto, A S Boutorine, R V Bensasson, M Prato
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Review

DNA-photocleavage agents

T Da Ros et al. Curr Pharm Des. 2001 Nov.

Abstract

This review describes recent advances in the development of DNA-photocleavage agents. Major mechanisms of photosensitized DNA photocleavage are presented and the most popular categories of compounds are considered, which include metal complexes and many organic functional derivatives. DNA-targeted conjugates of photosensitizers are also described and discussed.

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