Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support
- PMID: 11563152
- DOI: 10.1081/NCN-100002466
Step-by-step control by MALDI-TOF MS of an oligonucleotide synthesis on standard CPG solid-support
Abstract
MALDI-TOF mass spectrometry was used to monitor DNA solid-phase synthesis on long-chain alkylamine controlled-pore glass (LCAA-CPG) with a standard succinyl linker between the solid support and the growing oligonucleotide.
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