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. 1975 Apr;147(1):185-6.
doi: 10.1042/bj1470185.

Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver

M K Sardana, M R Satyanarayana Rao, G Padmanaban

Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver

M K Sardana et al. Biochem J. 1975 Apr.

Abstract

The porphyrogenic drug allylisopropylacetamide, a potent inducer of delta-aminolaevulinate synthetase, specifically increases nucleoplasmic RNA synthesis in rat liver. The drug-mediated increase in nucleoplasmic RNA synthesis is blocked by cycloheximide and haemin, which also inhibit the enzyme induction.

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