Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1975 Apr;147(1):185-6.
doi: 10.1042/bj1470185.

Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver

M K Sardana, M R Satyanarayana Rao, G Padmanaban

Effect of allylisopropylacetamide on Nuclear Ribonucleic Acid synthesis in rat liver

M K Sardana et al. Biochem J. 1975 Apr.

Abstract

The porphyrogenic drug allylisopropylacetamide, a potent inducer of delta-aminolaevulinate synthetase, specifically increases nucleoplasmic RNA synthesis in rat liver. The drug-mediated increase in nucleoplasmic RNA synthesis is blocked by cycloheximide and haemin, which also inhibit the enzyme induction.

PubMed Disclaimer

References

    1. Pharmacol Rev. 1967 Dec;19(4):523-57 - PubMed
    1. J Biochem. 1972 Sep;72(3):561-70 - PubMed
    1. Proc Natl Acad Sci U S A. 1967 May;57(5):1463-7 - PubMed
    1. Biochem J. 1971 Oct;124(4):767-77 - PubMed
    1. Biochim Biophys Acta. 1968 May 21;157(3):476-92 - PubMed