Effect of dihydroergocristine infusion on tolbutamide-induced insulin secretion in man
- PMID: 115708
- DOI: 10.1007/BF01964035
Effect of dihydroergocristine infusion on tolbutamide-induced insulin secretion in man
Abstract
The insulinemic response to 1 g of tolbutamide i.v. is greatly enhanced (+ 145%) after a 60-min infusion of the alpha-lytic dihydrogenated ergot alkaloid, dihydroergocristine (83.3 micrograms/min, corresponding to a total dose of 5 mg) in 7 healthy subjects. No differences are observed in the glycemic responses.