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. 2001 Sep 25;57(6):1124-6.
doi: 10.1212/wnl.57.6.1124.

Genome-wide scan for Parkinson's disease: the GenePD Study

A L DeStefano  1 , L I Golbe, M H Mark, A M Lazzarini, N E Maher, M Saint-Hilaire, R G Feldman, M Guttman, R L Watts, O Suchowersky, A L Lafontaine, N Labelle, M F Lew, C H Waters, J H Growdon, C Singer, L J Currie, G F Wooten, P Vieregge, P P Pramstaller, C Klein, J P Hubble, M Stacy, E Montgomery, M E MacDonald, J F Gusella, R H Myers
Affiliations

Genome-wide scan for Parkinson's disease: the GenePD Study

A L DeStefano et al. Neurology. .

Abstract

A genome-wide scan for idiopathic PD in a sample of 113 PD-affected sibling pairs is reported. Suggestive evidence for linkage was found for chromosomes 1 (214 cM, lod = 1.20), 9 (136 cM, lod = 1.30), 10 (88 cM, lod = 1.07), and 16 (114 cM, lod = 0.93). The chromosome 9 region overlaps the genes for dopamine beta-hydroxylase and torsion dystonia. Although no strong evidence for linkage was found for any locus, these results may be of value in comparison with similar studies by others.

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