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Review
. 2001 Sep 21;106(6):655-60.
doi: 10.1016/s0092-8674(01)00498-6.

Opening of the clamp: an intimate view of an ATP-driven biological machine

V Ellison  1 , B Stillman
Affiliations
Free article
Review

Opening of the clamp: an intimate view of an ATP-driven biological machine

V Ellison et al. Cell. .
Free article

Abstract

DNA polymerases require tethering to an accessory factor, typically a ring-shaped clamp, to remain bound to DNA during replication. Three recent structural studies provide unique insight into how these clamps are loaded onto DNA by the clamp loader machinery.

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