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Review
. 2001 Sep 21;106(6):661-73.
doi: 10.1016/s0092-8674(01)00492-5.

Switching and signaling at the telomere

E H Blackburn  1
Affiliations
Free article
Review

Switching and signaling at the telomere

E H Blackburn. Cell. .
Free article

Abstract

This review describes the structure of telomeres, the protective DNA-protein complexes at eukaryotic chromosomal ends, and several molecular mechanisms involved in telomere functions. Also discussed are cellular responses to compromising the functions of telomeres and of telomerase, which synthesizes telomeric DNA.

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