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Clinical Trial
. 2001 Jul:49:692-6.

A multicentric study with arteether in patients of uncomplicated falciparum malaria

O P Asthana  1 , J S Srivastava, V P Kamboj, N Valecha, V P Sharma, S Gupta, T K Pande, K A Vishwanathan, K M Mahapatra, N C Nayak, P K Mahapatra, J Mahanta, V K Srivastava, Vasdev, N Singh, M M Shukla, A B Balsara, S K Mishra, S K Satpathy, S Mohanty, B Dash
Affiliations
  • PMID: 11573553
Clinical Trial

A multicentric study with arteether in patients of uncomplicated falciparum malaria

O P Asthana et al. J Assoc Physicians India. 2001 Jul.

Abstract

Two hundred and sixty seven patients of uncomplicated P. falciparum malaria completed study in a multicentric phase III clinical trial of Arteether. Arteether was given intramuscularly in a dose of 150 mg daily for three consecutive days. Each patient was followed upto 28 days of alpha, beta arteether therapy. The cure rate was 97% with fever clearance time between 1-7 days (24-168 hours) and parasite clearance time between 1-3 days (24-72 hours). Parasite reappearance rate was found to be 3% and reported at only three of the centres. Following the treatment no adverse effect was observed on haematological, biochemical and vital clinical parameters.

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Comment in

  • Arteether in therapy of malaria.
    Thatte UM. Thatte UM. J Assoc Physicians India. 2001 Jul;49:687-91. J Assoc Physicians India. 2001. PMID: 11573552 No abstract available.