Guideline
doi: 10.1093/bja/86.2.283.
Guidelines for molecular genetic detection of susceptibility to malignant hyperthermia
Affiliations
- PMID: 11573677
- DOI: 10.1093/bja/86.2.283
Item in Clipboard
Guideline
Guidelines for molecular genetic detection of susceptibility to malignant hyperthermia
Br J Anaesth.
2001 Feb.
Free article
Abstract
Malignant hyperthermia (MH) is a potentially fatal pharmacogenetic disease triggered by several anaesthetic agents. The in vitro muscle contracture test (IVCT) is the standard test to establish an individual's risk of susceptibility to MH. Clinical practitioners and geneticists of the European MH Group have agreed on the present guidelines for the detection of MH susceptibility using molecular genetic techniques and/or IVCT to predict the risk of MH.
Comment in
-
A breakthrough in the genetic diagnosis of malignant hyperthermia.Br J Anaesth. 2001 Feb;86(2):166-8. doi: 10.1093/bja/86.2.166. Br J Anaesth. 2001. PMID: 11573654 Review. No abstract available.
Similar articles
-
Genotype-phenotype comparison of the Swiss malignant hyperthermia population.Hum Mutat. 2001 Oct;18(4):357-8. doi: 10.1002/humu.1203. Hum Mutat. 2001. PMID: 11668625 Clinical Trial.
-
Recent advances in the diagnosis of malignant hyperthermia susceptibility: how confident can we be of genetic testing?Eur J Hum Genet. 2003 Apr;11(4):342-8. doi: 10.1038/sj.ejhg.5200964. Eur J Hum Genet. 2003. PMID: 12700608
-
Determination of a positive malignant hyperthermia (MH) disposition without the in vitro contracture test in families carrying the RYR1 Arg614Cys mutation.Clin Genet. 2001 Aug;60(2):117-24. doi: 10.1034/j.1399-0004.2001.600205.x. Clin Genet. 2001. PMID: 11553045
-
[Current aspects of the diagnosis of malignant hyperthermia].Anaesthesist. 2002 Nov;51(11):904-13. doi: 10.1007/s00101-002-0390-x. Anaesthesist. 2002. PMID: 12434264 Review. German.
-
[Modern diagnostic approaches to malignant hyperthermia susceptibility].Anesteziol Reanimatol. 2014 Jul-Aug;59(4):64-8. doi: 10.18821/0201-7563-2014-59-4-64-68. Anesteziol Reanimatol. 2014. PMID: 25549489 Review. Russian.
Cited by
-
[Malignant hyperthermia. The ugly].Anaesthesist. 2007 Sep;56(9):923-9. doi: 10.1007/s00101-007-1218-5. Anaesthesist. 2007. PMID: 17565473 Review. German.
-
Functional analysis of ryanodine receptor type 1 p.R2508C mutation in exon 47.J Anesth. 2009;23(3):341-6. doi: 10.1007/s00540-009-0746-3. Epub 2009 Aug 14. J Anesth. 2009. PMID: 19685112
-
Genotyping of drug targets: a method to predict adverse drug reactions?Drug Saf. 2002;25(8):553-60. doi: 10.2165/00002018-200225080-00002. Drug Saf. 2002. PMID: 12113641 Review.
-
A case report of suspected malignant hyperthermia where patient survived the episode.Saudi J Anaesth. 2017 Apr-Jun;11(2):232-235. doi: 10.4103/1658-354X.203057. Saudi J Anaesth. 2017. PMID: 28442967 Free PMC article.
-
Evaluation of suspected malignant hyperthermia events during anesthesia.BMC Anesthesiol. 2013 Sep 23;13(1):24. doi: 10.1186/1471-2253-13-24. BMC Anesthesiol. 2013. PMID: 24053352 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
