Value of throat swab in diagnosis of melioidosis
- PMID: 11574624
- PMCID: PMC88440
- DOI: 10.1128/JCM.39.10.3801-3802.2001
Value of throat swab in diagnosis of melioidosis
Abstract
Throat swab (TS) cultures were performed for 1,011 patients with melioidosis and 3,524 healthy subjects or patients with other diseases. The specificity of TS culture for the diagnosis of melioidosis was 100%, and the overall sensitivity was 36% (24% for sputum-negative patients and 79% for sputum-positive patients). Direct plating of the TS specimen on Ashdown's medium was rapid (colonies were usually evident within 24 h) but only 63% sensitive compared to the results of primary culture in a selective broth. A throat swab should be cultured in all cases of suspected melioidosis.
References
-
- Ashdown L R. An improved screening technique for isolation of Pseudomonas pseudomallei from clinical specimens. Pathology. 1979;11:293–297. - PubMed
-
- Chaowagul W, White N J, Dance D A B, Wattanagoon Y, Naigowit P, Davis T M E, Looareesuwan S, Pitakwatchara N. Melioidosis: a major cause of community-acquired septicemia in northeastern Thailand. J Infect Dis. 1989;159:890–898. - PubMed
-
- Kanaphun P, Thirawattanasuk N, Suputtamongkol Y, Naigowit P, Dance D A B, Smith M D, White N J. Serology and carriage of Pseudomonas pseudomallei: a prospective study in 1000 hospitalized children in northeast Thailand. J Infect Dis. 1993;167:230–233. - PubMed
-
- Suputtamongkol Y, Chaowagul W, Chetchotisakd P, Lertpatanasuwun N, Intaranongpai S, Ruchutrakool T, Budhsarawong D, Mootsikapun P, Wuthiekanun V, Teerawatasook N, Lulitanond A. Risk factors for melioidosis and bacteremic melioidosis. Clin Infect Dis. 1999;29:408–413. - PubMed
-
- Walsh A L, Wuthiekanun V. The laboratory diagnosis of melioidosis. Br J Biomed Sci. 1996;53:249–253. - PubMed
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources