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Review
. 2001 Oct;108(7):957-62.
doi: 10.1172/JCI14122.

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

V A Fadok  1 , D L Bratton, P M Henson
Affiliations
Review

Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences

V A Fadok et al. J Clin Invest. 2001 Oct.
No abstract available

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Figures

Figure 1
Figure 1
A hypothetical model for the role of a newly described receptor for phosphatidylserine (PS) (26) in modulating inflammation and immune response. Engulfment of microbial organisms that fail to express PS externally does not engage the PS receptor (PSR); instead, receptors are stimulated by the microbe or its products that transduce proinflammatory signals. These include receptors for immunoglobulin, complement, collectins, endotoxin, etc. In contrast, when apoptotic cells are recognized, they expose PS, thus engaging the PSR, which provides an anti-inflammatory signal. TLR, toll-like receptor.
See this image and copyright information in PMC

References

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