Death signals changes in TFIID
- PMID: 11583609
- DOI: 10.1016/s1097-2765(01)00338-0
Death signals changes in TFIID
Abstract
In this issue of Molecular Cell, Bell et al. identify an isoform of hTAF(II)80 that is induced in response to several proapoptotic stimuli. The finding that extracellular signals can lead to changes in the subunit composition of TFIID provides an example of how regulated activity of the general transcription factors may contribute to inducible programs of gene expression.
Comment on
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Identification of hTAF(II)80 delta links apoptotic signaling pathways to transcription factor TFIID function.Mol Cell. 2001 Sep;8(3):591-600. doi: 10.1016/s1097-2765(01)00325-2. Mol Cell. 2001. PMID: 11583621
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