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. 2001 Sep;46(9):825-30.

Risk factors for antepartum fetal death

T Oron  1 , E Sheiner, I Shoham-Vardi, M Mazor, M Katz, M Hallak
Affiliations
  • PMID: 11584485

Risk factors for antepartum fetal death

T Oron et al. J Reprod Med. 2001 Sep.

Abstract

Objective: To determine the demographic, maternal, pregnancy-related and fetal risk factors for antepartum fetal death (APFD).

Study design: From our perinatal database between the years 1990 and 1997, 68,870 singleton birth files were analyzed. Fetuses weighing < 1,000 g at birth and those with structural malformations and/or known chromosomal anomalies were excluded from the study. In order to determine independent factors contributing to APFD, a multiple logistic regression model was constructed.

Results: During the study period there were 246 cases of APFD (3.6 per 1,000 births). The following obstetric factors significantly correlated with APFD in a multiple logistic regression model: preterm deliveries: small size for gestational age (SGA), multiparity (> 5 deliveries), oligohydramnios, placental abruption, umbilical cord complications (cord around the neck and true knot of cord), pathologic presentations (nonvertex) and meconium-stained amniotic fluid. APFD was not significantly associated with advanced maternal age.

Conclusion: APFD was significantly associated with several risk factors. Placental and umbilical cord pathologies might be the direct cause of death. Grand multiparity, oligohydramnios, meconium-stained amniotic fluid, pathologic presentations and suspected SGA should be carefully evaluated during pregnancy in order to decrease the incidence of APFD.

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