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Review
. 2001 Oct;17(10):S29-37.
doi: 10.1016/s0168-9525(01)02452-0.

Mouse models of cystic fibrosis

D J Davidson  1 , M Rolfe
Affiliations
Review

Mouse models of cystic fibrosis

D J Davidson et al. Trends Genet. 2001 Oct.

Abstract

The development of mouse models for cystic fibrosis has provided the opportunity to dissect disease pathogenesis, correlate genotype and phenotype, study disease-modifying genes and develop novel therapeutics. This review discusses the successes and the challenges encountered in characterizing and optimizing these models.

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