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Comment
. 2001 Oct;29(2):109-11.
doi: 10.1038/ng1001-109.

Islands of linkage disequilibrium

D B Goldstein
Comment

Islands of linkage disequilibrium

D B Goldstein. Nat Genet. 2001 Oct.

Abstract

A detailed knowledge of patterns of linkage disequilibrium in human populations is widely seen as a prerequisite for effective population-based disease gene mapping. New data suggest that linkage disequilibrium is highly structured into discrete blocks of sequence separated by hot spots of recombination.

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