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. 2001 Jul;18(4):729-36.
doi: 10.1081/cbi-100106084.

Cyclic red blood cell destruction in thalassemia

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Cyclic red blood cell destruction in thalassemia

U Giani et al. Chronobiol Int. 2001 Jul.

Abstract

A retrospective analysis of time series of hemoglobin (Hb) destruction of 24 children (11 males and 13 females) with thalassemia from the age of 6 to 12 years showed that the Hb destruction rate typically oscillated with an average period of 50 days. A possible relation between the periodism and the severity of the disease is also suggested.

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