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. 2001 Oct;94(10):551-9.
doi: 10.1093/qjmed/94.10.551.

Coagulopathy following lethal and non-lethal envenoming of humans by the South American rattlesnake (Crotalus durissus) in Brazil

I S Sano-Martins  1 , S C Tomy, D Campolina, M B Dias, S C de Castro, M C de Sousa-e-Silva, C F Amaral, N A Rezende, A S Kamiguti, D A Warrell, R D Theakston
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Coagulopathy following lethal and non-lethal envenoming of humans by the South American rattlesnake (Crotalus durissus) in Brazil

I S Sano-Martins et al. QJM. 2001 Oct.

Abstract

The South American tropical rattlesnake (Crotalus durissus subspp) is responsible for approximately 10% of bites from venomous snakes in Brazil. We studied 24 victims of bites by this species over 3 years, in south-eastern Brazil, particularly investigating haemostatic alterations. Thirteen patients were defined as moderately envenomed and 11 as severe. There were two deaths, which were not attributed to venom-induced haemostatic disturbances. However, envenoming by C. durissus is frequently associated with haemostatic disorders, which are probably attributable mainly to the action of the thrombin-like enzyme, with possible additional effects secondary to the powerful myotoxic activity of the venom.

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