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Review
. 2001 Nov;122(16):2005-11.
doi: 10.1016/s0047-6374(01)00304-9.

Cerebrospinal fluid tau and beta-amyloid(1-42) in dementia disorders

E Vanmechelen  1 , H Vanderstichele, F Hulstaert, N Andreasen, L Minthon, B Winblad, P Davidsson, K Blennow
Affiliations
Review

Cerebrospinal fluid tau and beta-amyloid(1-42) in dementia disorders

E Vanmechelen et al. Mech Ageing Dev. 2001 Nov.

Abstract

The reliability of cerebrospinal fluid (CSF)-tau and CSF-beta-amyloid assays for diagnosis of Alzheimer's disease and other dementing disorders such as frontotemporal dementia (FTD), dementia with Lewy bodies (DLB) and Creutzfeldt-Jakob disease (CJD) is reviewed. CSF assessment of the two proteins is useful in early diagnosis of AD and to differentiate it from FTD and DLB. Extremely high CSF-tau levels can discriminate CJD from AD.

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