Comparative Study
doi: 10.1136/jnnp.38.7.650.
Responses of isolated human basilar arteries to 5-hydroxytryptamine, noradrenaline, serum, platelets, and erythrocytes
- PMID: 1159436
- PMCID: PMC1083243
- DOI: 10.1136/jnnp.38.7.650
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Comparative Study
Responses of isolated human basilar arteries to 5-hydroxytryptamine, noradrenaline, serum, platelets, and erythrocytes
J Neurol Neurosurg Psychiatry.
1975 Jul.
Abstract
The isolated human basilar artery suspended in Kreb's solution contracts to 5-hydroxy-tryptamine, noradrenaline, and histamine, which stimulate specific receptors. Normal human serum contains an unidentified contractile substance, and erythrocytes relax the artery. Serum and erythrocytes potentiate 5-HT contractions. This preparation is suitable for studying vasoactive substances released during vasospasm after subarachnoid haemorrhage.
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