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Review
. 2001 Nov;39(11):1793-803.
doi: 10.1016/s0041-0101(01)00165-9.

Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century

R J Collier  1
Affiliations
Review

Understanding the mode of action of diphtheria toxin: a perspective on progress during the 20th century

R J Collier. Toxicon. 2001 Nov.

Abstract

Diphtheria toxin is one of the most extensively studied and well understood bacterial toxins. Ever since its discovery in the late 1800's this toxin has occupied a central focus in the field of toxinology. In this review, I present a chronology of major discoveries that led to our current understanding of the structure and activity of diphtheria toxin.

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