Genetic mutations occur gradually in in vivo populations of Mycobacterium tuberculosis bacteria

Comment

A S de Boer et al. J Clin Microbiol. 2001 Oct.

. 2001 Oct;39(10):3814.

doi: 10.1128/JCM.39.10.3814.2001.

No abstract available

Comment on

Genetic heterogeneity in Mycobacterium tuberculosis isolates reflected in IS6110 restriction fragment length polymorphism patterns as low-intensity bands.
de Boer AS, Kremer K, Borgdorff MW, de Haas PE, Heersma HF, van Soolingen D. de Boer AS, et al. J Clin Microbiol. 2000 Dec;38(12):4478-84. doi: 10.1128/JCM.38.12.4478-4484.2000. J Clin Microbiol. 2000. PMID: 11101583 Free PMC article.
Identification of a contaminating Mycobacterium tuberculosis strain with a transposition of an IS6110 insertion element resulting in an altered spoligotype.
Benjamin WH Jr, Lok KH, Harris R, Brook N, Bond L, Mulcahy D, Robinson N, Pruitt V, Kirkpatrick DP, Kimerling ME, Dunlap NE. Benjamin WH Jr, et al. J Clin Microbiol. 2001 Mar;39(3):1092-6. doi: 10.1128/JCM.37.3.1092-1096.2001. J Clin Microbiol. 2001. PMID: 11230432 Free PMC article.

1. Benjamin W H, Lok K H, Harris R, Brook N, Bond L, Mulcahy D, Robinson N, Pruitt V, Kirkpatrick D P, Kimerling M E, Dunlap N E. Identification of a contaminating Mycobacterium tuberculosis strain with a transposition of an IS6110insertion element resulting in an altered spoligotype. J Clin Microbiol. 2001;39:1092–1096. - PMC - PubMed
1. de Boer A S, Kremer K, Borgdorff M W, de Haas P E W, Heersma H, van Soolingen D. Genetic heterogeneity in Mycobacterium tuberculosis isolates reflected in IS6110restriction fragment length polymorphism patterns as low-intensity bands. J Clin Microbiol. 2001;38:4478–4484. - PMC - PubMed
1. de Boer A S, Borgdorff M W, de Haas P E W, Nagelkerke N J D, van Embden J D A, van Soolingen D. Rate of change of IS6110 genotypes of Mycobacterium tuberculosisbased on serial patient isolates. J Infect Dis. 1999;180:1238–1244. - PubMed