Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity
- PMID: 11600237
- DOI: 10.1016/s0223-5234(01)01252-1
Synthesis of some triazolyl-antipyrine derivatives and investigation of analgesic activity
Abstract
The synthesis of some triazolyl-antipyrine derivatives starting from 4-chloroacetamidoantipyrine and 3-(aryloxyalkyl)-4-ethyl/phenyl-5-mercapto-1,2,4-triazoles is described. The chemical structures of the compounds were elucidated by IR, 1H-NMR and mass spectral studies. These compounds were tested for analgesic activity.
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