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Comment
. 2001 Nov;64(1):1-3.
doi: 10.1093/toxsci/64.1.1.

Toxicant-induced oxidative stress in cancer

B L Upham  1 , J G Wagner
Affiliations
Comment

Toxicant-induced oxidative stress in cancer

B L Upham et al. Toxicol Sci. 2001 Nov.

Abstract

The article highlighted in this issue is "The Role of Oxidative Stress in Indium Phosphide-Induced Lung Carcinogenesis in Rats" by Barbara C. Gottschling, Robert R. Maronpot, James R. Hailey, Shyamal Peddada, Cindy R. Moomaw, James E. Klaunig, and Abraham Nyska (pp. 28-40). The article integrates a traditional pathologic study of toxicant-induced pulmonary carcinogenesis with an immunohistologic assessment of oxidative stress, thereby determining a potential mechanism of action of a toxicant, specifically indium phosphide.

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