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Case Reports
. 2001 Nov;45(5):767-70.
doi: 10.1067/mjd.2001.117398.

Pemphigus foliaceus developing after metastasis of cutaneous squamous cell carcinoma to regional lymph nodes

M Inaoki  1 , K Kaji, S Furuse, A Fujimoto, N Komatsu, M Takata, K Takehara
Affiliations
Case Reports

Pemphigus foliaceus developing after metastasis of cutaneous squamous cell carcinoma to regional lymph nodes

M Inaoki et al. J Am Acad Dermatol. 2001 Nov.

Abstract

We describe a patient in whom pemphigus foliaceus developed after cutaneous squamous cell carcinoma (SCC) metastasized to regional lymph nodes. Immunologic analysis revealed that production of anti-desmoglein 1 autoantibodies started when SCC metastasized, and the SCC expressed desmoglein 1, suggesting a pathogenic role of metastasized SCC in developing pemphigus foliaceus.

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