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Case Reports
. 1975 Sep;20(9):808-12.
doi: 10.1007/BF01070948.

Familial pseudomembranous colitis and its relation to lincomycin therapy

Case Reports

Familial pseudomembranous colitis and its relation to lincomycin therapy

M J Harrod et al. Am J Dig Dis. 1975 Sep.

Abstract

Severe pseudomembranous colitis was observed in 3 members of a single family: the father and 2 of his children. 2 of the affected family members received the antibiotic lincomycin prior to the onset of their symptoms. The findings in this family raise the possibility that antibiotic-induced pseudomembranous colitis in some patients may be the result of a pharmacogenetic interaction.

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References

    1. JAMA. 1973 Mar 19;223(12):1379-80 - PubMed
    1. Lancet. 1974 May 4;1(7862):878-9 - PubMed
    1. Radiology. 1973 Aug;108(2):263-8 - PubMed
    1. N Engl J Med. 1974 Apr 11;290(15):841-3 - PubMed
    1. Am J Gastroenterol. 1970 Sep;54(3):214-28 - PubMed

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