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. 1982 May 1;1(8279):1028-9.
doi: 10.1016/s0140-6736(82)92036-0.

Death of patient who was unwitting subject of randomised controlled trial of cancer treatment

Diana Brahams

Death of patient who was unwitting subject of randomised controlled trial of cancer treatment

Diana Brahams. Lancet. .

Abstract

KIE: A British case of an elderly widow who received an experimental cancer drug without her consent is reported. The drug led to her death and the case came to public notice. It was revealed that, since 1980, 250 patients were allocated by random selection into one of three experimental groups without being informed that research was underway. Suggestions are made for eliminating deception or nondisclosure in therapeutic trials.

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