doi: 10.1007/BF00691796.
Correlative studies of axonal spheroids and Lafora-like bodies in aged dogs
- PMID: 116474
- DOI: 10.1007/BF00691796
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Correlative studies of axonal spheroids and Lafora-like bodies in aged dogs
Acta Neuropathol.
1979 Oct.
Abstract
The gracile nucleus and conus medullaris, the sites of predilection for spheroids and Lafora-like bodies, were examined light and electron microscopically in 91 dogs ranging from 1 month to 19 years of age. The number of both structures showed a tendency to increase with age. Spheroids have already been found in younger dogs before the appearance of Lafora-like bodies. In the aged dog, intra-spheroidal Lafora-like bodies were occasionally observed. Correlative studies may yield clues on the pathogenesis of aging phenomena in the CNS.
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