Termination sites for adenovirus type 2 DNA replication
- PMID: 1165592
- PMCID: PMC354733
- DOI: 10.1128/JVI.16.4.759-766.1975
Termination sites for adenovirus type 2 DNA replication
Abstract
Termination sites for replication of adenovirus type 2 DNA have been demonstrated at both ends of the viral chromosome by the procedure of Danna and Nathans (1972). Single-stranded DNA from replicating intermediates was also characterized by hybridization with separated strands of viral DNA. The results indicate that both strands are exposed during replication.
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