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Review
. 2001 Oct 16;11(20):R842-4.
doi: 10.1016/s0960-9822(01)00500-0.

DNA replication: partners in the Okazaki two-step

S A MacNeill  1
Affiliations
Free article
Review

DNA replication: partners in the Okazaki two-step

S A MacNeill. Curr Biol. .
Free article

Abstract

The correct processing of Okazaki fragments during lagging-strand DNA replication has a vital role in maintaining genome integrity. Recent findings suggest that, in eukaryotes, the processing of Okazaki fragments occurs by a two-step mechanism governed by the single-stranded DNA binding factor RPA.

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