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. 2001 Nov;16(11):2418-21.
doi: 10.1093/humrep/16.11.2418.

Prevalence and risk factors of adenomyosis at hysterectomy

T Bergholt  1 , L Eriksen, N Berendt, M Jacobsen, J B Hertz
Affiliations

Prevalence and risk factors of adenomyosis at hysterectomy

T Bergholt et al. Hum Reprod. 2001 Nov.

Abstract

Background: The present study was performed to evaluate the prevalence and possible associated risk factors for adenomyosis.

Methods: Medical records were retrieved and histo-pathological material re-examined for 549 consecutive women undergoing hysterectomy in a two-year period from 1990-1991.

Results: The prevalence of adenomyosis in the study varied from 10.0-18.2%, depending on different diagnostic criteria. The presence of endometrial hyperplasia at the time of hysterectomy was the only variable significantly associated with adenomyosis (OR = 3.0; 95% CI: 1.2-8.3). No statistically significant association was found between adenomyosis and previous caesarean section, endometrial curettage or evacuation of the uterus. Furthermore, we did not see any significant association between adenomyosis and pain-related symptoms, indication for hysterectomy, age, parity or number of myometrial samples.

Conclusions: Our study stresses the need for precise diagnostic criteria for adenomyosis, and furthermore indicates that endometrial hyperplasia and adenomyosis may have a common aetiology.

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