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. 1975 Feb 21;187(4177):654-5.
doi: 10.1126/science.1167977.

Concanavalin A: its action in inducing Oocyte maturation-inducing substance in starfish follicle cells

J Kubota, H Kanatani

Concanavalin A: its action in inducing Oocyte maturation-inducing substance in starfish follicle cells

J Kubota et al. Science. .

Abstract

Maturation of starfish oocytes is induced by 1-methyladenine produced in follicle cells under the influence of a gonad-stimulating hormonal peptide released from the nervous system. Concanavalin A stimulates isolated follicle cells to produce 1-methyladenine, which suggests that it has the same capacity as the peptide hormone to indirectly induce oocyte maturation.

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