Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2001 Dec;11(6):627-34.
doi: 10.1016/s0959-437x(00)00245-8.

Genome-wide variation in the human and fruitfly: a comparison

C F Aquadro  1 , V Bauer DuMont, F A Reed
Affiliations
Review

Genome-wide variation in the human and fruitfly: a comparison

C F Aquadro et al. Curr Opin Genet Dev. 2001 Dec.

Abstract

Average levels of nucleotide diversity are ten-fold lower in humans than in the fruitfly, Drosophila melanogaster. Despite this difference, apparently as a result of a lower population size, patterns of genomic diversity are strikingly similar in being correlated with local rates of recombination, and influenced by similar interactions between positive natural selection and recombination. Both species also show lower levels of variation on average in non-African compared to African populations, reflecting a similar evolutionary history and perhaps both natural selection and founder effects in new environments.

PubMed Disclaimer

LinkOut - more resources