E1A is an oncogene and may immortalize normal cells, especially in combination with other oncoproteins
- PMID: 11689591
- DOI: 10.1200/JCO.2001.19.21.4183
E1A is an oncogene and may immortalize normal cells, especially in combination with other oncoproteins
Comment on
-
Cationic liposome-mediated E1A gene transfer to human breast and ovarian cancer cells and its biologic effects: a phase I clinical trial.J Clin Oncol. 2001 Jul 15;19(14):3422-33. doi: 10.1200/JCO.2001.19.14.3422. J Clin Oncol. 2001. PMID: 11454891 Clinical Trial.
Similar articles
-
Therapeutic transfer of DNA encoding adenoviral E1A.Recent Pat Anticancer Drug Discov. 2007 Jan;2(1):1-10. doi: 10.2174/157489207779561471. Recent Pat Anticancer Drug Discov. 2007. PMID: 18221050 Review.
-
The erbB2 gene as a cancer therapeutic target and the tumor- and metastasis-suppressing function of E1A.Cancer Metastasis Rev. 1998 Jun;17(2):195-202. doi: 10.1023/a:1006054421970. Cancer Metastasis Rev. 1998. PMID: 9770116 Review. No abstract available.
-
A novel apoptotic mechanism of genetically engineered adenovirus-mediated tumour-specific p53 overexpression through E1A-dependent p21 and MDM2 suppression.Eur J Cancer. 2012 Sep;48(14):2282-91. doi: 10.1016/j.ejca.2011.12.020. Epub 2012 Jan 13. Eur J Cancer. 2012. PMID: 22244827
-
Impact of E1a modifications on tumor-selective adenoviral replication and toxicity.Mol Ther. 2004 Oct;10(4):749-57. doi: 10.1016/j.ymthe.2004.07.014. Mol Ther. 2004. PMID: 15451459
-
Liposome-mediated in vivo E1A gene transfer suppressed dissemination of ovarian cancer cells that overexpress HER-2/neu.Oncogene. 1995 Oct 5;11(7):1383-8. Oncogene. 1995. PMID: 7478560
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical