Review
doi: 10.1016/s0955-0674(00)00278-7.
Putting the stress on senescence
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- PMID: 11698192
- DOI: 10.1016/s0955-0674(00)00278-7
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Review
Putting the stress on senescence
Curr Opin Cell Biol.
2001 Dec.
Erratum in
- Curr Opin Cell Biol 2002 Feb;14(1):123
Abstract
Cultivation of primary cells over many generations eventually results in a reproducible loss of proliferative potential that has been termed 'replicative senescence'. Recent work has revealed the heterogeneity of senescence. Importantly, the analysis of the various aspects and types of senescence has turned out to be very informative about numerous in vivo processes, and particularly about carcinogenesis.
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