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. 1975 Jun;27(3):391-4.
doi: 10.1099/0022-1317-27-3-391.

Modifications of cellular RNA-polymerase II after infection with frog virus 3

Modifications of cellular RNA-polymerase II after infection with frog virus 3

G Campadelli-Fiume et al. J Gen Virol. 1975 Jun.

Abstract

RNA-polymerase II extracted from FV3-infected and uninfected BHK cells were compared by measuring their abilities to bind [3-H]-amanitin and ribonucleoside triphosphates. Binding sites for [3-H]-amanitin and the dissociation constant of the complex between [3H]-amanitin and RNA-polymerase II were significantly modified following FV3 infection. The apparent Km's for ribonucleoside triphosphates remained unchanged.

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