Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2001 Nov 3;358(9292):1515-6.
doi: 10.1016/s0140-6736(01)06576-x.

Urothelial malignant disease and Chinese herbal nephropathy

G M Lord, T Cook, V M Arlt, H H Schmeiser, G Williams, C D Pusey
Case Reports

Urothelial malignant disease and Chinese herbal nephropathy

G M Lord et al. Lancet. .

Abstract

We have previously reported occurrence of a specific type of nephropathy due to ingestion of Chinese herbs (Chinese herbal nephropathy [CHN]) in two patients in the UK. These cases highlighted the role of aristolochic acid in causing this nephropathy, which was first described in a Belgian cohort. We now report development of invasive transitional cell carcinoma of the urinary tract associated with the presence of aristolochic acid-DNA adducts in one of these patients. This work clearly shows the carcinogenic potential of aristolochic acid in this new type of nephropathy.

PubMed Disclaimer

Comment in

  • Chinese herbal nephropathy.
    Lampert N, Xu Y. Lampert N, et al. Lancet. 2002 Mar 2;359(9308):796-7. doi: 10.1016/S0140-6736(02)07852-2. Lancet. 2002. PMID: 11888616 No abstract available.

MeSH terms

LinkOut - more resources