[Effect of Urapidil in antihypertensive therapy of preeclampsia on newborns]

Abstract

Objective: For the therapy of preeclamptic patients is Urapidil besides Dihydralazine another possible option for iv-therapy with good results in first clinical studies. Effects of both drugs on the newborns were observed. -

Methods: The maternal and fetal Urapidil plasma-concentrations and cardiovascular parameters of the newborns were observed in a randomised comparative therapy-study. -

Results: We found low fetal Urapidil plasma-concentrations as well as a less influence on cardiovascular parameters compared to dihydralazine. -

Discussion: With Urapaidil we have another therapeutic option in preeclampsia where we could not show any negative side-effects on the newborns.