Evidence for two active X chromosomes in a human XXY triploid
- PMID: 1171078
- DOI: 10.1007/BF00272480
Evidence for two active X chromosomes in a human XXY triploid
Abstract
A human XXY chromatin negative triploid culture has been found to have both the A and B isozymes of glucose-6-phosphate dehydrogenase, as well as an intermediately migrating AB (hybrid) band. This finding indicates that the cells in this culture each possess 2 active X chromosomes. Possible mechanisms producing the abnormalities seen in this disorder are presented and discussed.