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. 1975 May 26;28(1):39-42.
doi: 10.1007/BF00272480.

Evidence for two active X chromosomes in a human XXY triploid

Evidence for two active X chromosomes in a human XXY triploid

D D Weaver et al. Humangenetik. .

Abstract

A human XXY chromatin negative triploid culture has been found to have both the A and B isozymes of glucose-6-phosphate dehydrogenase, as well as an intermediately migrating AB (hybrid) band. This finding indicates that the cells in this culture each possess 2 active X chromosomes. Possible mechanisms producing the abnormalities seen in this disorder are presented and discussed.

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