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Review
. 2001 Dec;9(12):3077-92.
doi: 10.1016/s0968-0896(01)00176-6.

Carbohydrate mimetics-based glycosyltransferase inhibitors

P Compain  1 , O R Martin
Affiliations
Review

Carbohydrate mimetics-based glycosyltransferase inhibitors

P Compain et al. Bioorg Med Chem. 2001 Dec.

Abstract

The search for carbohydrate mimetics-based glycosyltransferase inhibitors is a dynamic field that emerged 10 years ago. This review presents a description of the different types of glycosyltransferase inhibitors containing a carbohydrate mimetic (primarily an iminosugar, a carbasugar or a C-glycoside) and data on their biological activity whenever such data are available. The purpose of this account is to foster a synergy between the two expanding research areas of glycomimetics and glycosyltransferases.

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