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. 2001;101(10):37-9.

[Nervous tissue protein autoantibodies in hepatolenticular degeneration]

[Article in Russian]
S G Morozov, M P Usanova, V V Poleshchuk, A V Poletaev, I A Ivanova-Smolenskaia, E D Markova
  • PMID: 11712267

[Nervous tissue protein autoantibodies in hepatolenticular degeneration]

[Article in Russian]
S G Morozov et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2001.

Abstract

Two novel protein antigens-Hbmp-1 and Hbmp-2 have been isolated from human brain tissue. Test-systems for determining auto-antibodies (a-Ab) to above mentioned proteins, as well as to basic myelin protein, S-100 beta and glial fibrillary acid protein have been developed. Sixty-three HLD patients have been examined. Increased a-Ab levels to the novel proteins has been shown in HLD patients; no difference between HLD patients and control groups being found for a-Ab levels to other proteins. Correlation has been observed between a type and course of the disease, on the one hand, and a-Ab levels to Hbmp-1 and to Hbmp-2, on the other hand.

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