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. 2001 Nov;139(5):734-7.
doi: 10.1067/mpd.2001.118398.

Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants

C Imrie  1 , M Rowland, B Bourke, B Drumm
Affiliations

Limitations to carbon 13-labeled urea breath testing for Helicobacter pylori in infants

C Imrie et al. J Pediatr. 2001 Nov.

Abstract

We determined the validity of the carbon 13-labeled urea breath test in young children. We found that although the 13C-labeled urea breath test had a specificity greater than 90%, borderline or false positive results occurred more frequently in children younger than 2 years compared with older children. False positive results may be caused by oral-urease-producing organisms because direct intragastric administration of 13C urea reduced the excess delta 13CO2. Care is urged in interpreting one positive 13C-labeled urea breath test in children younger than 2 years.

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